Brain science’s biggest roadblock: Collecting better data without killing people

Historically, there has been no safe, non-invasive and/or efficient method with deep penetration for modulating the human brain in vivo—stimulating or suppressing certain brain processes in a living person. Ultrasound, however, offers a promising approach, especially when used in combination with other non-invasive techniques. Ultrasound—a decades-proven technique in which the echoes of high-frequency sound waves off internal body tissue are converted into sonogram images—can safely penetrate the human skull and be focused in different regions of the brain, probing responses. The penetration is on the order of several centimeters and can cover the entire brain. The weakness of the ultrasound…

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